Preimplantation Genetic Diagnosis (PGD), also called Preimplantation Genetic Screening (PGS), is a procedure used prior to implantation to help in identifying genetic defects within embryos created through in vitro fertilization to prevent certain diseases or disorders from being passed on to the child. In most cases, the female, male, or both partners have been genetically screened and identified to be carriers of potential problems. Here one of the 8 cells (Blastomere) is aspirated using specific pipette, used for PGD, with the help of micromanipulator (same equipment used for ICSI). Then the single cell is subjected for genetic testing utilizing their DNA chain to gain further information. If the cell seems to be normal then the embryo is declared as fit ones to transfer in to the uterus. Further research in this field is going on in our centre with respect to this particular modality. CGH - Comparative Genomic Hybridization is the upcoming test for the same purpose.